O-016 Thrombus permeability is associated with distinct proteomic features and differential susceptibility to adamts13 thrombolysis

ConclusionThrombus permeability is associated with distinguishable proteomics features, including greater abundance of platelet-related proteins in highly permeable clots and monocyte/macrophages in less permeable clots. These findings also suggest that highly pervious thrombi may be differentially susceptible to ADAMTS13 augmented thrombolysis.Disclosures D. Schartz: None. S. Akkipeddi: None. N. Ellens: None. R. Rahmani: None. G. Kohli: None. R. Ismail: None. S. Chittaranjan: None. K. Welle: None. T. Bhalla: None. T. Mattingly: None. C. Morrell: None. M. Bender: None.

http://jnis.bmj.com/cgi/content/short/15/Suppl_1/A13-b?rss=1

Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Schartz, D., Akkipeddi, S., Ellens, N., Rahmani, R., Kohli, G., Ismail, R., Chittaranjan, S., Welle, K., Bhalla, T., Mattingly, T., Morrell, C., Bender, M. Tags: SNIS 20th annual meeting oral abstracts Source Type: research