Bench to Bedside

In this issue of The Journal of Molecular Diagnostics, Wan et al describe an alternative method in the diagnosis of Leber hereditary optic neuropathy (LHON) variants using a rapid and convenient system with a low limit of detection that can be readily integrated into clinical practice.1 This method utilizes clustered regularly interspaced short palindromic repeats (CRISPR)/Cas –based nucleic acid detection technology combined with enzymatic recombinase amplification to provide a visual detection system for the three LHON primary variants.

Source: Journal of Molecular Diagnostics - July 29, 2023 Category: Pathology Authors: Benjamin Hilton Tags: Commentary Source Type: research