Caring for Patients With Congenital Adrenal Hyperplasia Throughout the Lifespan

Obstet Gynecol. 2023 Aug 1;142(2):257-268. doi: 10.1097/AOG.0000000000005263. Epub 2023 Jul 5.ABSTRACTCongenital adrenal hyperplasia (CAH) is an autosomal recessive disorder affecting cortisol and aldosterone biosynthesis, which can lead to virilization in fetuses with a 46,XX karyotype. 21-hydroxylase deficiency is the most common cause of CAH, accounting for 90-99% of all patients with the condition. The management of patients with CAH should be done with a multidisciplinary team, which would address all of the complex components of their care throughout their lifespans. Many multidisciplinary teams have adopted shared decision-making approaches to genital surgery in which parents and patients can be part of the decision-making process. Continued research is needed to best serve these patients throughout their lifespans.PMID:37473408 | DOI:10.1097/AOG.0000000000005263

Source: Obstetrics and Gynecology - July 20, 2023 Category: OBGYN Authors: Noor Zwayne Reeti Chawla Kathleen van Leeuwen Source Type: research