The Genetic Testing Reference Materials (GeT-RM) Coordination Program: Over 10 years of support for pharmacogenomic testing

The Genetic Testing Reference Materials (GeT-RM) Coordination Program was established in 2004 at the Centers for Disease Control and Prevention (CDC), which has consistently operated collaboratively with the genetic testing community to characterize publicly available genomic DNA reference materials.1 The Program was initially centered on characterizing reference materials for Mendelian genetic disorders commonly tested by clinical laboratories; however, in 2010 the GeT-RM reported the first collaborative effort to characterize five clinically actionable genes implicated in interindividual drug response variability: CYP2D6, CYP2C19, CYP2C9, VKORC1, and UGT1A1.
Source: Journal of Molecular Diagnostics - Category: Pathology Authors: Tags: Commentary Source Type: research