Modulation of tumor-associated macrophage activity with radiation therapy: a  systematic review

ConclusionTAMs seem to have an ambivalent role on the efficacy of cancer treatment. Radiation therapy, which exerts its main antitumor activity via cell killing, can in turn interfere with TAM characterization through different modalities. The plasticity of TAMs makes them an attractive target for anticancer therapies and more research should be conducted to explore this potential therapeutic strategy.
Source: Strahlentherapie und Onkologie - Category: Cancer & Oncology Source Type: research