Pruritus: An Approach to Diagnosis and Management for the Inpatient Dermatologist

AbstractPurpose of ReviewThis review provides a framework to categorize causes of pruritus that may present in the inpatient dermatology setting and highlights therapeutic options for these pruritic conditions.Recent FindingsVarious pruritogens have been implicated in dermatologic and systemic diseases, and itch characteristics may differ depending on etiology. Biologics have emerged as effective therapies for pruritus associated with dermatologic conditions. Novel treatment options for pruritus associated with systemic diseases include difelikefalin for CKD pruritus, butorphanol and ileal bile acid transporters for cholestatic pruritus, and biologics for several systemic etiologies.SummaryPruritus has multiple etiologies, is often difficult to diagnose and treat, and can have a significant impact on quality of life. Various pruritic conditions may present in the inpatient setting, and dermatologists should be able to effectively diagnose and manage these patients.

Source: Current Dermatology Reports - June 30, 2023 Category: Dermatology Source Type: research