Monozygotic twins with identical premature timing of acne onset: A Case report

This report describes a pair of monozygotic twin brothers with identical premature onset of acne, who were found to have an identical homozygous mutation in the promoter region of the CYP21A2 gene. While it is widely known that NCCAH is associated with genetic changes, the drive behind onset of adrenarche are widely unknown. As such, this report provokes thoughts on whether adrenarche could be influenced by adrenal genetic polymorphisms.PMID:37387304 | DOI:10.1111/ajd.14117
Source: The Australasian Journal of Dermatology - Category: Dermatology Authors: Source Type: research