High-Temporal-Resolution Lung Kinetic Modeling Using Total-Body Dynamic PET with Time-Delay and Dispersion Corrections

Conclusion: Corrections to the input function are important for accurate lung kinetic analysis of HTR dynamic PET data. The modeling of both delay and dispersion can improve model fitting and significantly impact quantification of $${K}_{1}$$, $${K}_{\hbox{ i }}$$, and $${v}_{\hbox{ b }}$$.

Source: Journal of Nuclear Medicine - June 30, 2023 Category: Nuclear Medicine Authors: Wang, Y., Spencer, B. A., Schmall, J., Li, E., Badawi, R. D., Jones, T., Cherry, S. R., Wang, G. Tags: Clinical Investigations Source Type: research