Five new sesquiterpenoids from agarwood of Aquilaria sinensis

Abstract
Five new eudesmane-type sesquiterpenoids (aquisinenoids F–J (1–5)) and five known compounds (6–10) were isolated from the agarwood of Aquilaria sinensis. Their structures, including absolute configurations, were identified by comprehensive spectroscopic analyses and computational methods. Inspired by our previous study on the same kinds of skeletons, we speculated that the new compounds have anticancer and anti-inflammatory activities. The results did not show any activity, but they revealed the structure–activity relationships (SAR).

Beilstein J. Org. Chem. 2023, 19, 998–1007. doi:10.3762/bjoc.19.75

Source: Beilstein Journal of Organic Chemistry - June 30, 2023 Category: Chemistry Authors: Beilstein Journal of Organic Chemistry - Syndicated Feeds Tags: agarwood Aquilaria sinensis SAR studies sesquiterpenoids Full Research Paper Source Type: research