Decoding a ribosome uncertainty

Trends Genet. 2023 Jun 26:S0168-9525(23)00132-4. doi: 10.1016/j.tig.2023.06.001. Online ahead of print.ABSTRACTThe ribosome is among the most ancient macromolecular complexes. Throughout evolution, the function of the ribosome has remained essential and conserved: the decoding of an mRNA template with tRNA-linked amino acids, to synthesize a protein. In a recent study, Holm et al. capture evolutionary distinctions in the structure and kinetics of 'mRNA decoding' by the human ribosome.PMID:37380507 | DOI:10.1016/j.tig.2023.06.001

Source: Trends in Genetics : TIG - June 28, 2023 Category: Genetics & Stem Cells Authors: Olivier Duss Rainer Nikolay Matthew L Kraushar Source Type: research