Synergising single-cell resolution and 4sU labelling boosts inference of transcriptional bursting

Despite the recent rise of RNA-seq datasets combining single-cell (sc) resolution with 4-thiouridine (4sU) labelling, analytical methods exploiting their power to dissect transcriptional bursting are lacking. ...

Source: Genome Biology - June 16, 2023 Category: Genetics & Stem Cells Authors: David M. Edwards, Philip Davies and Daniel Hebenstreit Tags: Method Source Type: research