Pseudomonas —Spectrum of Disease Presentations for the Inpatient Dermatologist

AbstractPurpose of ReviewPseudomonas aeruginosa-associated cutaneous dermatoses are reasons for consultation for the inpatient dermatologist. This review provides an overview of the spectrum of Pseudomonas-associated cutaneous diseases that may present in the inpatient setting along with the diagnostic work-up and clinical management.Recent FindingsPseudomonas aeruginosa infections are an ongoing healthcare concern due to its intrinsic and acquired antimicrobial resistance. The rising incidence of multi-drug resistantP. aeruginosa strains has led to the prioritization and development of effective drugs with increased efforts towards antibiotic stewardship. Diagnostic and clinical management forP. aeruginosa infections include blood and tissue culture and, in immunocompromised or severely ill patients, the use of 2 antipseudomonal agents with de-escalation once the culture and antibiotic susceptibilities become available.SummaryPseudomonas aeruginosa is frequently considered among the differential diagnosis of causative pathogens in inpatient cutaneous infections, most importantly due to its associated high morbidity and mortality. The disease presentation spans various anatomical locations, and the clinical course may be difficult to manage due to antibiotic resistance. Clinicians should be familiar with the spectrum of disease presentations as well as the appropriate diagnostic work-up and management strategies.
Source: Current Dermatology Reports - Category: Dermatology Source Type: research