Opportunities and Challenges of Kava in Lung Cancer Prevention

This article will review the epidemiological data, pre-clinical animal data, and limited clinical data that support the potential of kava in reducing human lung cancer risk via its holistic polypharmacological effects. To facilitate its future clinical translation, advanced knowledge is needed with respect to its mechanisms of action and the development of mechanism-based non-invasive biomarkers in addition to safety and efficacy in more clinically relevant animal models.PMID:37298489 | DOI:10.3390/ijms24119539

Source: Cancer Control - June 10, 2023 Category: Cancer & Oncology Authors: Breanne Freeman Jessica Mamallapalli Tengfei Bian Kayleigh Ballas Allison Lynch Alexander Scala Zhiguang Huo Kristianna M Fredenburg Adriaan W Bruijnzeel Carolyn J Baglole Junxuan Lu Ramzi G Salloum John Malaty Chengguo Xing Source Type: research