P204 Changes of lymphocyte susceptibility to glucocorticoids in cystic fibrosis patients with Burkholderia cepacia

Recently we have shown decreased IL-17F levels in blood and sputum samples of CF patients, chronically colonized with Burkholderia cepacia complex (Bcc)1. Since IL-17F is a cytokine upregulating the expression of cellular glucocorticoid β-receptors, its deficiency may change steroid sensitivity in various tissues and organs.

Source: Journal of Cystic Fibrosis - June 1, 2023 Category: Respiratory Medicine Authors: V. Shmarin, D. Pukhalskaya, S. Krasovsky, L. Avakyan, S. Semykin, Z. Kirill, E. Kondratieva, N. Kashirskaya, G. Shmarina Tags: Posters Source Type: research