FBXO22 mediates the NGF/TRKA signaling pathway in bone metastases in prostate cancer

This study aims to explore the biological function of E3 ubiquitin ligase F-box only protein 22 (FBXO22) in PC metastasis and its specific regulation mechanism. It was revealed by transcriptome sequencing that FBXO22 was overexpressed in PC tissues (versus adjacent tissues) and bone tissues (versus biopsied bone tissues without bone metastases).

Source: American Journal of Pathology - June 8, 2023 Category: Pathology Authors: Yuehua Zhang, Wen Li, Shenghu Guo, Zheng Wu, Lei Zhang, Ya Liu, Xing Li, Xiaojin Guo, Jing Cao, Chunwang Yang, Zhiyu Wang Tags: Regular Article Source Type: research