Epiphany: predicting Hi-C contact maps from 1D epigenomic signals

Recent deep learning models that predict the Hi-C contact map from DNA sequence achieve promising accuracy but cannot generalize to new cell types and or even capture differences among training cell types. We ...

Source: Genome Biology - June 6, 2023 Category: Genetics & Stem Cells Authors: Rui Yang, Arnav Das, Vianne R. Gao, Alireza Karbalayghareh, William S. Noble, Jeffery A. Bilmes and Christina S. Leslie Tags: Method Source Type: research