Declining autozygosity over time: An exploration in over 1 million individuals from three diverse cohorts

This study found that genome-wide autozygosity is decreasing over generational time in three large cohorts of diverse genetic ancestries, though the rate of this decline varies by country and ancestry. This trend is most likely attributable to increases in urbanization and panmixia.

Source: The American Journal of Human Genetics - May 12, 2023 Category: Genetics & Stem Cells Authors: Sarah M.C. Colbert, Frank R. Wendt, Gita A. Pathak, Drew A. Helmer, Elizabeth R. Hauser, Matthew C. Keller, Renato Polimanti, Emma C. Johnson Tags: Report Source Type: research