Conformational antigenic heterogeneity as a cause of the persistent fraction in HIV-1 neutralization

Neutralizing antibodies (NAbs) protect against HIV-1 acquisition in animal models and show promise in treatment of infection. They act by binding to the viral envelope glycoprotein (Env), thereby blocking its ...

Source: Retrovirology - May 27, 2023 Category: Virology Authors: Philippe Colin, Rajesh P. Ringe, Anila Yasmeen, Gabriel Ozorowski, Thomas J. Ketas, Wen-Hsin Lee, Andrew B. Ward, John P. Moore and P. J. Klasse Tags: Research Source Type: research