MiR-29b modulates DNA methylation in promoter region of miR-130b in mouse model of Diabetic nephropathy

In conclusion, miR-29b expression was found to modulate DNA methylation via DNMTs and regulate methylation of miR-130b. The result of this study provides a future direction to unveil role of miRNA expression in DNA methylation and its consequent effect on other miRNAs in DN.
Source: Journal of Diabetes and Metabolic Disorders - Category: Endocrinology Source Type: research