Positive effect of leptin substitution on mood and behaviour in patients with congenital leptin deficiency

ConclusionsMetreleptin substitution improved indices of physical activity and psychological wellbeing in patients with CLD. This suggests that reduced leptin concentrations might be in part responsible for emotional and behavioural changes seen during starvation.

Source: Pediatric Obesity - May 25, 2023 Category: Eating Disorders & Weight Management Authors: Julia Schnurbein, Miriam Remy, Stephanie Brandt, Jaida Manzoor, Katja Kohlsdorf, Saqib Mahmood, Johannes Hebebrand, Martin Wabitsch Tags: ORIGINAL RESEARCH Source Type: research