The neglected twin: Nummular eczema is a variant of atopic dermatitis with codominant TH2/TH17 immune response
Noncommunicable inflammatory skin diseases (ncISD) are a frequently occurring heterogenous group of skin disorders with complex immune-mediated pathogenesis accompanied by impaired quality of life and social stigmatization. Atopic dermatitis (AD), a major representative of ncISD, comprises a diverse group of diseases in terms of clinical, histologic, and molecular hallmarks, with common overlapping morphologic features.1 However, we lack a clear definition for most of those entities, including nummular eczema (NE).
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Alexander B öhner, Manja Jargosch, Nikola S. Müller, Natalie Garzorz-Stark, Caroline Pilz, Felix Lauffer, Rosi Wang, Sophie Roenneberg, Alexander Zink, Jenny Thomas, Fabian J. Theis, Tilo Biedermann, Stefanie Eyerich, Kilian Eyerich Source Type: research