Epigenetic reprogramming of Runx3 reinforces CD8  + T-cell function and improves the clinical response to immunotherapy

Checkpoint blockade immunotherapy, represented by PD-1 or PD-L1 antibody treatment, has been of tremendous success in clinical practice. However, the low clinical response rate and lack of biomarkers for predi...

Source: Molecular Cancer - May 16, 2023 Category: Cancer & Oncology Authors: Zongzhi Liu, Xiang Li, Yibo Gao, Jiejie Liu, Yating Feng, Yang Liu, Junyun Wang, Chunmeng Wang, Dongrui Wang, Jie He, Weidong Han, Qian Mei and Yingli Sun Tags: Research Source Type: research