The MMP-2 histone H3 N-terminal tail protease is selectively targeted to the transcription start sites of active genes

Proteolysis of the histone H3 N-terminal tail (H3NT) is an evolutionarily conserved epigenomic feature of nearly all eukaryotes, generating a cleaved H3 product that is retained in  ~ 5–10% of the genome. Altho...

Source: Epigenetics and Chromatin - May 10, 2023 Category: Genetics & Stem Cells Authors: Benjamin H. Weekley and Judd C. Rice Tags: Research Source Type: research