Crystallographic study of a novel DNA-binding domain of human HLTF involved in the template-switching pathway to avoid the replication arrest caused by DNA damage

In this study, the HIRAN domain of human HLTF was successfully crystallized. The crystals belonged to space group P41212 or P43212, with unit-cell parameters a = b = 130.0, c = 150.1 Å.

Source: Acta Crystallographica Section F - May 20, 2015 Category: Biochemistry Authors: Ikegaya, Y.Hara, K.Hishiki, A.Yokoyama, H.Hashimoto, H. Tags: HIRAN domain HLTF template switching DNA-binding domain research communications Source Type: research