Antibodies cross-reactive with DNase1L3 and dsDNA discovered

Nature Reviews Rheumatology, Published online: 10 May 2023; doi:10.1038/s41584-023-00977-7Clinical and molecular analysis of autoantibodies against the endonuclease DNase1L3 in patients with systemic lupus erythematosus led to the identification of a subset of pathogenetic antibodies that are cross-reactive with double-stranded DNA.

Source: Nature Reviews Rheumatology - May 10, 2023 Category: Rheumatology Authors: Sarah Onuora Source Type: research