PKM2/STAT1-mediated PD-L1 upregulation on neutrophils during sepsis promotes neutrophil organ accumulation by serving an anti-apoptotic role

Delayed neutrophil apoptosis during sepsis may impact neutrophil organ accumulation and tissue immune homeostasis. Elucidating the mechanisms underlying neutrophil apoptosis may help identify potential therape...

Source: Journal of Inflammation - May 2, 2023 Category: Allergy & Immunology Authors: Yinjiaozhi Li, Ruoming Tan, Ranran Li, Rui Tian, Zhaojun Liu, Xiaoli Wang, Erzhen Chen, Tingting Pan and Hongping Qu Tags: Research Source Type: research