Classification and Epidemiologic Aspects of Acute-on-Chronic Liver Failure

The three most common definitions of acute-on-chronic liver failure (ACLF) are derived from data from North America, Europe, and the Asian-Pacific Region. All three definitions identify patients with underlying liver disease who are at increased risk for mortality who develop a syndrome often characterized by associated organ failures. The epidemiology of ACLF differs throughout various regions globally and is driven by the cause of the underlying chronic liver disease and the triggers of ACLF.

Source: Clinics in Liver Disease - April 23, 2023 Category: Gastroenterology Authors: Zaid H. Tafesh, Raquel Olivo Salcedo, Nikolaos Pyrsopoulos Source Type: research