Primary adenocarcinoma of the bladder: a rare primary bladder tumour type

Primary bladder adenocarcinoma is rare and metastatic or locally invasive adenocarcinomas from other organs are more frequently seen within the bladder. Here we present a 61-year-old patient with an adenocarcinoma within the bladder neck. It was a diagnostic challenge to differentiate between primary bladder adenocarcinoma, metastatic colorectal adenocarcinoma, and prostatic adenocarcinoma. After extensive immunohistochemistry the diagnosis of primary bladder adenocarcinoma was made. We discuss how to come to this diagnosis and what immunohistochemistry approaches can be taken to differentiate it from other adenocarcinomas.

Source: Diagnostic Histopathology - April 12, 2023 Category: Pathology Authors: Kate Marks, Alireza Behzadnia, Jo-An Roulson Tags: Short case Source Type: research