IRAK-M has effects in regulation of lung epithelial inflammation

CONCLUSION: Our findings suggested that IRAK-M has effect on lung epithelial inflammation with an influence on epithelial secretion of CXCL10 partly mediated through JNK and p38 MAPK pathways. IRAK-M modulation might indicate a new insight into asthma pathogenesis from disease origin.PMID:37029363 | DOI:10.1186/s12931-023-02406-5

Source: Respiratory Care - April 7, 2023 Category: Respiratory Medicine Authors: Jia Li Zhoude Zheng Yi Liu Hongbing Zhang Youming Zhang Jinming Gao Source Type: research