Roflumilast enhances the melanogenesis and attenuates oxidative stress-triggered damage in melanocytes

The management of vitiligo is challenging due to limited treatment options, and therapeutic strategy varies according to the active or stable stage of vitiligo. PDE4 inhibitor has been used to treat various skin diseases, but the efficacy in vitiligo treatment is mixed.

Source: Journal of Dermatological Science - April 3, 2023 Category: Dermatology Authors: Zile Chen, Yiting Li, Yongyi Xie, Shu Nie, Bin Chen, Zhouwei Wu Source Type: research