Parmoferone A, a new depsidone from the lichen < em > Parmotrema cristiferum < /em >

Nat Prod Res. 2023 Mar 31:1-6. doi: 10.1080/14786419.2023.2193746. Online ahead of print.ABSTRACTA new depsidone, parmoferone A (1), together with three known compounds, parmosidone K (2), albifolione (3), and 4-chloroorcinol (4) were isolated from the lichen Parmotrema cristiferum (Taylor) Hale (Parmeliaceae). The structures of isolated compounds were identified from its spectroscopic data and by comparison with the literature. Compounds 1-4 were evaluated for alpha-glucosidase inhibition. Compound 1 was determined to be a potent non-competitive inhibitor against alpha-glucosidase with an IC50 value of 18.1 μM.PMID:36999530 | DOI:10.1080/14786419.2023.2193746

Source: Natural Product Research - March 31, 2023 Category: Biochemistry Authors: Thuc-Huy Duong Tran Nguyen Minh An Thi-Kim-Dung Le Thi-Minh-Dinh Tran Huy Truong Nguyen Thi Hong Anh Nguyen Ngoc-Hong Nguyen Jirapast Sichaem Source Type: research