Foveal photoreceptor disruption in ocular diseases: An optical coherence tomography-based differential diagnosis

Fovea centralis, an area 1.5 mm in diameter located at the center of the macula lutea, contains the highest concentration of cone photoreceptors and is primarily responsible for central visual acuity.41 Histological analysis provided invaluable insights on the development and structural organization of the fovea wherein during gestation and early infancy, peripheral displacement of the inner retinal layers with resultant centrally packed cone cells are seen.30 The advent of optical coherence tomography (OCT) revolutionized retinal imaging, thereby providing non-invasive, high-resolution cross-sectional images that correlated well with the histological findings.

Source: Survey of Ophthalmology - March 17, 2023 Category: Opthalmology Authors: Sumit Randhir Singh, Harshit Vaidya, Enrico Borrelli, Jay Chhablani Tags: Review article Source Type: research