Effect of Food on the Pharmacokinetics and Pharmacodynamics of a Novel Dual Delayed ‐Release Formulation of Esomeprazole in Healthy Subjects

In conclusion, although the systemic exposure of esomeprazole decreased when DR esomeprazole was administered in the fed state compared to that in the fasted state, the degree of gast ric acid secretion inhibition was not clinically different, regardless of food intake.
Source: Clinical Pharmacology in Drug Development - Category: Drugs & Pharmacology Authors: Tags: Original Article Source Type: research