FSIP2 plays a role in the acrosome development during spermiogenesis

Conclusion
Our findings unveil that FSIP2 might involve in sperm acrosome development, and consequently, its mutations might contribute to globozoospermia or acrosomal aplasia. We meanwhile first uncover the potential molecular mechanism of FSIP2 regulating acrosome biogenesis.

Source: Journal of Medical Genetics - February 23, 2023 Category: Genetics & Stem Cells Authors: Zheng, R., Wang, Y., Li, Y., Guo, J., Wen, Y., Jiang, C., Yang, Y., Shen, Y. Tags: Genotype-phenotype correlations Source Type: research