Prostaglandin E2 prevents radiotherapy-induced alopecia by attenuating transit amplifying cell apoptosis through promoting G1 arrest

Growing hair follicles (HFs) harbor actively dividing transit amplifying cells (TACs), rendering them highly sensitive to radiotherapy (RT). Clinically, there is still a lack of treatment options for radiotherapy-induced alopecia (RIA).

Source: Journal of Dermatological Science - February 20, 2023 Category: Dermatology Authors: Shih-Fan Lai, Wen-Yen Huang, Wei-Hung Wang, Jin-Bon Hong, Sung-Hsin Kuo, Sung-Jan Lin Source Type: research