Radiation-Induced Pulmonary Fibrosis: Roles of Therapy-Induced Senescence and microRNAs

CONCLUSION: Our analysis of the published literature in the last decade on RIPF, miRNA, and TIS identifies TIS as a mechanism in the onset and progression of RIPF, which is regulated through several miRNAs. This work may lead to the discovery and development of the next generation of miRNA therapeutics and/or the repurposing of approved pharmaceutical agents and the development of early biomarker panels to predict RIPF.PMID:36763093 | DOI:10.1080/09553002.2023.2177768

Source: International Journal of Radiation Biology - February 10, 2023 Category: Radiology Authors: Pataje G S Prasanna Molykutty Aryankalayil Deborah E Citrin C Norman Coleman Source Type: research