Low dose vancomycin-loaded spacers for two-stage revision knee arthroplasty: High success, low toxicity

Two-stage revision arthroplasty is a widely used treatment method for infected knee arthroplasty. Loading high doses of antibiotics to spacer during the first stage is standard practice. However, there are reported systemic side effects attributed to antibiotic-loaded spacers. The aim of our study is to investigate the success rate and systemic toxicity following the first stage revision knee arthroplasty with low-dose vancomycin-loaded spacers.
Source: The Knee - Category: Orthopaedics Authors: Source Type: research