Human buccal epithelium acquires microbial hyporesponsiveness at birth, a role for secretory leukocyte protease inhibitor

Conclusions
We identify SLPI as a new player in acquisition of microbial hyporesponsiveness by buccal and intestinal epithelium in the first weeks after microbial colonisation.

Source: Gut - May 8, 2015 Category: Gastroenterology Authors: Menckeberg, C. L., Hol, J., Simons-Oosterhuis, Y., Raatgeep, H. C., de Ruiter, L. F., Lindenbergh-Kortleve, D. J., Korteland-van Male, A. M., El Aidy, S., van Lierop, P. P. E., Kleerebezem, M., Groeneweg, M., Kraal, G., Elink-Schuurman, B. E., de Jongste, Tags: Crohn's disease Gut microbiota Source Type: research