Statistical phasing of 150,119 sequenced genomes in the UK Biobank

We present an open-source pipeline for filtering, phasing, and indexing 150,119  UK Biobank genomes. This pipeline makes it possible to apply haplotype-based methods to these data. We use the pipeline to phase 406 million single-nucleotide variants on chromosomes 1–22 and X at a cost of £2,309.

Source: The American Journal of Human Genetics - November 29, 2022 Category: Genetics & Stem Cells Authors: Brian L. Browning, Sharon R. Browning Tags: Report Source Type: research