Efficient generation of epigenetic disease model mice by epigenome editing using the piggyBac transposon system

Epigenome-edited animal models enable direct demonstration of disease causing epigenetic mutations. Transgenic (TG) mice stably expressing epigenome-editing factors exhibit dramatic and stable changes in targe...

Source: Epigenetics and Chromatin - December 16, 2022 Category: Genetics & Stem Cells Authors: Takuro Horii, Sumiyo Morita, Mika Kimura and Izuho Hatada Tags: Methodology Source Type: research