Radotinib attenuates TGF β -mediated pulmonary fibrosis in vitro and in vivo: exploring the potential of drug repurposing

Tyrosine kinase (TK) plays a crucial role in the pathogenesis of idiopathic pulmonary fibrosis. Here, we aimed to investigate whether radotinib (Rb) could inhibit pulmonary fibrosis by inhibiting TK in vitro a...

Source: BMC Clinical Pharmacology - December 15, 2022 Category: Drugs & Pharmacology Authors: Suji Baek, Seung Hae Kwon, Joo Yeong Jeon, Gong Yeal Lee, Hyun Soo Ju, Hyo Jung Yun, Dae Jin Cho, Kang Pa Lee and Myung Hee Nam Tags: Research Source Type: research