Fc γRIIB inhibits inflammation in a murine model of psoriasis

Psoriasis is a chronic, inflammatory cutaneous disease. Fc γRIIB is a low-affinity receptor for the IgG Fc fragment that provides a negative feedback pathway to down-regulate B-cell antigen receptor signaling.

Source: Journal of Dermatological Science - December 12, 2022 Category: Dermatology Authors: Irisu Nakabori, Yasuhito Hamaguchi, Kaori Sawada, Motoki Horii, Natsumi Fushida, Tasuku Kitano, Wang Chenyang, Jia Xibei, Yuichi Ikawa, Akito Komuro, Takashi Matsushita Source Type: research