Small extracellular vesicle targeting of hypothalamic AMPK α1 promotes weight loss in leptin receptor deficient mice

Leptin receptor (LEPR) deficiency promotes severe obesity and metabolic disorder. However, the current therapeutic options against this syndrome are scarce.

Source: Metabolism - Clinical and Experimental - November 21, 2022 Category: Biomedical Science Authors: Edward Milbank, Nathalia Dragano, Xavi Vidal-Gomez, Ver ónica Rivas-Limeres, Pablo Garrido-Gil, Mireille Wertheimer, Sylvain Recoquillon, María P. Pata, José Luis Labandeira-Garcia, Carlos Diéguez, Rubén Nogueiras, M. Carmen Martínez, Ramaroson Andr Source Type: research