A Micro-Costing Framework for Circulating Tumor DNA Testing in Dutch Clinical Practice

Circulating tumor DNA (ctDNA) is a promising new biomarker with multiple potential applications in cancer care. Estimating total cost of ctDNA testing is necessary for reimbursement and implementation, but challenging because of variations in workflow. We aimed to develop a micro-costing framework for consistent cost calculation of ctDNA testing. First, the foundation of the framework was built, based on the complete step-wise diagnostic workflow of ctDNA testing. Second, the costing method was set up, including costs for personnel, materials, equipment, overhead, housing, and failures.

Source: Journal of Molecular Diagnostics - November 16, 2022 Category: Pathology Authors: Astrid Kramer, Ed Schuuring, Daan C.L. Vessies, Paul van der Leest, Maartje J. Geerlings, Pim Rozendal, Mirthe Lanfermeijer, Theodora C. Linders, L éon C. van Kempen, Remond J.A. Fijneman, Marjolijn J.L. Ligtenberg, Gerrit A. Meijer, Daan van den Broek, Tags: Regular article Source Type: research