ΔNp63α transcriptionally represses p53 target genes involved in the radiation-induced DNA damage response

The DNA damage response (DDR) is a mechanism that protects cells against radiation-induced oxidative DNA damage by causing cell cycle arrest and apoptosis. TP63 is a member of the tumour suppressor TP53 gene fami...

Source: Radiation Oncology - November 15, 2022 Category: Cancer & Oncology Authors: Ken-ichi Kudo, Naohiro Tsuyama, Kento Nagata, Tatsuhiko Imaoka, Daisuke Iizuka, Misaki Sugai-Takahashi, Moe Muramatsu and Akira Sakai Tags: Research Source Type: research