Prehospital Tranexamic Acid in Major Pediatric Trauma Within a Physician-Led Emergency Medical Services System: A Multicenter Retrospective Study
Objectives:
Describe prehospital tranexamic acid (TXA) use and appropriateness within a major trauma pediatric population, and identify the factors associated with its use.
Design:
Multicenter, retrospective study, 2014–2020.
Setting:
Data were extracted from a multicenter French trauma registry including nine trauma centers within a physician-led prehospital emergency medical services (EMS) system.
Patients:
Patients less than 18 years old were included. Those who did not receive prehospital intervention by a mobile medical team and those with missing data on TXA administration were excluded.
Interventions:
None.
Measurements and Main Results:
Nine-hundred thirty-four patients (median [interquartile range] age: 14 yr [9–16 yr]) were included, and 68.6% n = 639) were male. Most patients were involved in a road collision (70.2%, n = 656) and suffered a blunt trauma (96.5%; n = 900). Patients receiving TXA (36.6%; n = 342) were older (15 [13–17] vs 12 yr [6–16 yr]) compared with those who did not. Patient severity was higher in the TXA group (Injury Severity Score 14 [9–25] vs 6 [2–13]; p
Source: Pediatric Critical Care Medicine - Category: Pediatrics Tags: Online Clinical Investigations Source Type: research