Vaccines for the prevention of COVID-19 in older adults

Institutionalized and community-dwelling older adults have been greatly impacted by the COVID-19 pandemic with increased morbidity and mortality. The advent of vaccines and their widespread use in this population has brought about a dramatic turnaround in COVID-19 outcomes. The immunogenicity and effectiveness of the various vaccine options worldwide will be discussed. Optimization of vaccine usage will still be important to maximize protection due to reduced initial immunity, development of variant strains, and fading of immunity over time. There are also lessons learned specific to older populations for future pandemics of novel pathogens where there is minimal to no prior immunity.
Source: Infectious Diseases Clinics of North America - Category: Infectious Diseases Authors: Source Type: research