[ASAP] Optimization of Pyrimidine Compounds as Potent JAK1 Inhibitors and the Discovery of R507 as a Clinical Candidate

ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.2c00411

Source: ACS Medicinal Chemistry Letters - October 25, 2022 Category: Chemistry Authors: Yan Chen, Hui Li, Rose Yen, Thilo J. Heckrodt, Darren McMurtrie, Rajinder Singh, Vanessa Taylor, Esteban S. Masuda, Gary Park, and Donald G. Payan Source Type: research