Mucoepidermoid Carcinoma of the Palate in Adolescence
CONCLUSIONS: A CNB to confirm mammographic or clinical findings of breast lesions is an accurate method to establish a pathological diagnosis of breast lesions. The accuracy is higher for invasive carcinomas than for non-invasive cancers. Excisional biopsies are necessary for lesions with anticipated sampling errors or when the core needle biopsy findings are discordant with clinical or mammographic findings. PMID: 30109786 [PubMed - in process]
The oral therapy lenvatinib joins sorafenib as the only drugs approved for first-line treatment of patients with unresectable hepatocellular carcinoma.FDA Approvals
Publication date: Available online 16 August 2018Source: European Journal of Surgical OncologyAuthor(s): Serge Evrard
Condition: Recurrent Hepatocellular Carcinoma Intervention: Biological: LioCyx Sponsors: Lion TCR Pte. Ltd.; Agency for Science, Technology and Research Not yet recruiting
Conditions: RCC; Clear Cell Renal Cell Carcinoma; Kidney Cancer; Renal Cancer; Renal Cell Carcinoma; Renal Cell Cancer Metastatic; Renal Cell Carcinoma Recurrent; Renal Cell Cancer, Recurrent; Kidney Intervention: Drug: PT2977 in combination with cabozantinib tablets Sponsor: Peloton Therapeutics, Inc. Not yet recruiting
Conditions: Human Papillomavirus-Related Carcinoma; Human Papillomavirus-Related Cervical Carcinoma; Stage IB2 Cervical Cancer AJCC v8; Stage II Cervical Cancer AJCC v8; Stage II Vaginal Cancer AJCC v8; Stage IIA Cervical Cancer AJCC v8; Stage IIA Vaginal Cancer AJCC v8; Stage IIA1 Cervical Cancer AJCC v8; Stage IIA2 Cervical Cancer AJCC v8; Stage IIB&...
Conditions: Non-Small Cell Lung Carcinoma; Pulmonary Nodule; Stage I Lung Cancer AJCC v8; Stage IA1 Lung Cancer AJCC v8; Stage IA2 Lung Cancer AJCC v8; Stage IA3 Lung Cancer AJCC v8; Stage IB Lung Cancer AJCC v8; Stage II Lung Cancer AJCC v8; Stage IIA Lung Cancer AJCC v8; Stage IIB Lung Cancer AJCC v8 Interventions: Other: B...
Conditions: Cutaneous Melanoma; Non-small Cell Lung Cancer; Squamous Cell Carcinoma of the Head and Neck; Urothelial Carcinoma; Renal Cell Carcinoma Interventions: Biological: GEN-009 Adjuvanted Vaccine; Drug: Nivolumab Sponsor: Genocea Biosciences, Inc. Recruiting
Conclusion: Together, we provide the first evidence that BCYRN1 plays an oncogenic role in CRC cells. BCYRN1 may be a promising prognostic biomarker and a potential therapeutic target for CRC.Cell Physiol Biochem 2018;48:2337 –2349
CONCLUSION: Cyclooxygenase-2 over-expression increases during normal-adenoma-carcinoma sequence, moreover COX-2 over-expression is associated with advanced tumor stage and Ki67 over-expression. These findings suggest a significant role of COX-2 in the carcinogenesis and prognosis of CRC in our study population. PMID: 30106414 [PubMed - in process]