Challenges in integrating molecular profiles into clinical cancer care

SummaryProfiling of malignancies with next-generation sequencing (NGS) is now routine in clinical practice. While many cases of approved targeted therapies are straightforward based on well-characterized alterations, applying large NGS multigene panels to therapeutic use is frequently challenging. In this article, variant interpretation, therapy matching, and final treatment selection challenges are discussed.
Source: Memo - Magazine of European Medical Oncology - Category: Cancer & Oncology Source Type: research